Perimenopause is a profound transitional phase. For many women, it brings a mix of physical and emotional symptoms that can disrupt daily life. Fatigue becomes harder to shake. Mood swings feel unpredictable. Brain fog dulls clarity and focus. Sleep becomes elusive, even after a long day. These changes can feel overwhelming. You are not alone if you are wondering whether there is a better way to navigate this transition—one that does not involve synthetic hormones or one-size-fits-all solutions.
The good news is that effective, natural remedies for perimenopause symptoms do exist. Functional medicine offers a science-based approach that supports your body’s innate ability to balance hormones, repair tissues, and build resilience. This is the approach I have used with thousands of women in my clinical practice and is the foundation of the Perimenopause Support Bundle, a comprehensive solution featuring The Myers Way® Multivitamin, EstroProtect, Adrenal Support, and Spectrum 5 Collagen™. This physician-formulated system targets the root causes of perimenopausal symptoms, providing the support your body needs to restore energy, clarity, and well-being.
Why Natural Remedies Work for Perimenopause
Perimenopause is not a hormonal shutdown. Rather, it is a time of fluctuation. Estrogen, progesterone, and other hormones begin to rise and fall unpredictably, leading to a variety of symptoms. Supporting your body during this time means helping it adapt to these changes.
Natural remedies work by supporting your body’s own hormone production and detoxification pathways. They promote adrenal balance, liver detoxification, nervous system regulation, and collagen production. Each system plays a role in your overall hormone health.
Effective support is comprehensive. It goes beyond just managing symptoms and instead addresses the underlying causes. By nourishing your body with targeted nutrients and botanicals, you help it regain balance from the inside out. If you're wondering how to manage perimenopause naturally, this approach offers an empowering option.
Top 7 Natural Remedies for Perimenopause
Let us explore the most effective, research-backed natural solutions that can help restore balance and reduce symptoms, without relying on synthetic hormones.

1. Support Estrogen Metabolism with EstroProtect
One of the most common root causes of perimenopausal symptoms is estrogen dominance. This occurs when estrogen levels are not effectively detoxified by the liver, leading to issues such as weight gain, breast tenderness, mood swings, and irregular cycles.
EstroProtect is designed to support healthy estrogen metabolism and cellular health.† It contains DIM (diindolylmethane) and calcium D-glucarate, two potent nutrients that enhance both phase I and phase II detoxification in the liver. This allows your body to break down and eliminate excess estrogen more effectively.
By clearing out estrogen in a safe, natural way, EstroProtect helps restore hormonal balance and reduce many of the uncomfortable symptoms of perimenopause.
2. Nourish Hormones with The Myers Way® Multivitamin
Hormonal health begins with nutrient sufficiency. Many women are deficient in the key vitamins and minerals required for healthy adrenal, thyroid, and hormone function. This becomes even more important during perimenopause, as your body’s demand for these nutrients increases.
The Myers Way® Multivitamin offers high-potency, bioavailable forms of B vitamins, antioxidants, and trace minerals that support hormonal regulation, energy metabolism, and immune resilience. It is an excellent foundation for any woman over the age of 35.
Unlike standard multivitamins, this physician-formulated blend is designed to support the unique needs of women going through perimenopause and menopause. Supporting your stress response also brings relief to many menopausal symptoms.
3. Balance Stress with Adrenal Support
Chronic stress can exacerbate hormone imbalances. When cortisol is elevated due to emotional or physical stress, it can suppress progesterone, disrupt sleep, and amplify fatigue.
Adrenal Support offers a blend of adaptogenic herbs and essential nutrients that promote a balanced stress response. Ingredients such as ashwagandha, rhodiola, licorice root, and vitamin C work synergistically to stabilize cortisol and support adrenal function.
This formula helps reduce the highs and lows of energy, mood, and sleep, often triggered by cortisol imbalances.
4. Strengthen Skin, Joints, and Immunity with Spectrum 5 Collagen™
Collagen production declines significantly during perimenopause.(1) This leads to thinning hair, brittle nails, joint stiffness, and more visible signs of aging, such as fine lines and wrinkles.
Spectrum 5 Collagen™ is a physician-formulated, multi-source collagen blend that supports the strength and integrity of your hair, skin, nails, joints, and gut lining. This full-body support promotes resilience at a time when tissue repair and regeneration begin to slow.
By restoring your body’s collagen reserves, you can maintain physical comfort and confidence throughout the perimenopausal years.
5. Sleep Support: Rest and Restore with Melatonin
Sleep disturbances are one of the most frustrating aspects of perimenopause. Hormonal changes affect circadian rhythms, making it harder to fall and stay asleep. Poor sleep also increases cortisol(2), which can further worsen hormonal symptoms.
A gentle melatonin supplement, paired with calming botanicals such as lemon balm, chamomile, and passionflower, can help reset your natural sleep patterns and support deeper, more restorative sleep.
This approach helps you wake up refreshed and ready to face the day, even during the most challenging phases of hormonal change.
6. Nervous System and Mood Support: NeuroCalm Mag
Many women experience increased anxiety, irritability, or brain fog during perimenopause. This is often due to declining estrogen’s effect on neurotransmitters and nervous system function.(3)
NeuroCalm Mag provides a gentle, highly absorbable form of magnesium L-threonate, along with co-factors that support neurotransmitter balance and brain function. This formula helps with anxiety, improving cognitive clarity, and stabilizing mood, without the side effects of pharmaceutical interventions.
By calming the nervous system, NeuroCalm Mag makes it easier to cope with the mental and emotional challenges of perimenopause.
7. Bone Health and Hormone Harmony: Vitamin D3/K2 and OsteoDura™
Bone loss accelerates during perimenopause due to declining estrogen levels. Without proactive support, women are at increased risk for osteoporosis and fractures.(4)
Liquid Vitamin D3 with K2 supports calcium absorption and directs it into bones rather than soft tissues. OsteoDura™ complements this by providing bioavailable calcium, magnesium, boron, and other bone-supporting minerals.
Together, these supplements build bone density, flexibility, and strength while also supporting immune health and hormone production. Targeted nutrients and lifestyle habits such as exercise and hormone-balancing foods are also essential during this stage.
Consistency and Patience
Supporting your body through perimenopause and menopause is not an overnight fix. While natural approaches can be powerful, they require consistency. Nutrients, herbs, and collagen-based support compounds typically work best when taken daily over time. Sticking with your protocol, rather than stopping and starting. This allows your body to recalibrate, rebuild reserves, and adapt to changing hormone levels more effectively.
The goal isn’t to eliminate every symptom instantly, but to create steady, sustainable progress toward balance.
Why the AMMD™ Perimenopause Bundle Is the Complete Solution
While you can piece together support for one product at a time, the Perimenopause Support Bundle is physician-designed to address all the root causes simultaneously.
This bundle includes:
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The Myers Way® Multivitamin for foundational nutrient support
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EstroProtect for healthy estrogen metabolism
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Adrenal Support for balanced cortisol and sustained energy
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Spectrum 5 Collagen™ for skin, joint, and tissue resilience
Each formula was created by a functional medicine physician with a deep understanding of the interconnected systems involved in perimenopause. The bundle saves time, removes guesswork, and ensures your body gets the comprehensive support it needs.
It is ideal for women who are ready to take a proactive, natural approach to hormone health and overall wellness, especially those seeking real results in the perimenopause and menopause transition.
Reclaim Your Energy and Confidence
Natural remedies for perimenopause offer a powerful path forward. You do not have to settle for discomfort, confusion, or synthetic hormone treatments that may not align with your goals.
By supporting your body’s hormone metabolism, nutrient levels, adrenal resilience, and collagen repair, you empower it to regain balance and thrive during this transition.
Begin with a comprehensive, science-backed solution such as the Perimenopause Support Bundle. With functional medicine on your side, you can reclaim your energy, sharpen your focus, stabilize your mood, and feel like yourself again.
You deserve to feel vibrant and supported through every stage of life.
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