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The 5 Best Supplements for Autoimmune Disease

July 9th, 2019

“Which supplements should I take?” was one of the most common questions asked by my patients with autoimmunity. Today I’ll cover the 5 supplements that I think are the best for autoimmune disease.

As I explain in The Autoimmune Solution, if you are dealing with autoimmunity, the source of your condition is a glitch in your immune system. Environmental factors such as diet, a leaky gut, toxins, infections, and stress lead your immune system to attack your own tissues.

It could be your thyroid being attacked, or your joints under fire, or symptoms associated with your condition on your skin. No matter what particular organ or tissue is attacked, your immune system is doing the firing. By supporting rather than suppressing your immune system, you are able to eliminate symptoms and reverse your condition.

Whether it’s Hashimoto’s, Graves’, lupus, rheumatoid arthritis, psoriasis, fibromyalgia, or any of the other many autoimmune diseases, there are 5 key supplements that I recommend. These supplements all work to optimize your immune system so that it is no longer attacking your own body. Additionally, when taken together, 3 of these supplements—glutathione, curcumin, and resveratrol—potentiate one another, making their effects more powerful!

You can watch and listen to this Facebook Live that describes the potentiation of these supplements.

To get your immune system in optimal condition, here are my top 5 supplements for autoimmunity.

1. Glutathione

Glutathione is your body’s primary detoxifier. It plays a crucial role in helping your immune system fight off infections. While it is concentrated in your liver, glutathione is also in every cell in your body. The three key amino acids in glutathione—cysteine, glycine, and glutamate—help bind free radicals and toxins to safely and effectively flush them out of your system.

Your body produces some glutathione naturally. However, a poor diet, exposure to toxins, medications, stress, and illness deplete your glutathione levels or stop production altogether.

Depleted glutathione levels factor into triggering your body’s inflammatory response, and could lead to autoimmune diseases including rheumatoid arthritis, Crohn’s disease, and multiple sclerosis.1 Without enough glutathione, your body cannot properly detox and the toxins linger in your bloodstream or get stored in fat. This wreaks havoc on your immune system and sets you up for chronic illness.2

I recommend a glutathione supplement for those with autoimmunity, toxic mold, heavy metal overload, or general toxin exposure. Glutathione is so powerful that I even recommend it to anyone who wants to reach peak optimal health. However, I tried a LOT of different types of glutathione, especially when I dealt with mold exposure. It is very challenging to get a form of glutathione that actually works, and it’s important to stay informed about the best sources available.

Glutathione Sources

Intravenous (IV) glutathione supplementation is considered the gold standard. On the other hand, it is expensive and it can be inconvenient. Then there are oral supplements, which are readily available, though not commonly found in the liposomal or acetylated form. These typically break down before your body can properly utilize them.

The “liposomal” form of glutathione is in a fat-soluble membrane that helps protect it from breaking down in the gut, so it can effectively penetrate your cell walls. However, after working with thousands of patients, I recommend the “acetylated” form over all others. Your body easily absorbs it without breaking it down. Adding an acetyl group makes the glutathione molecule more stable and enhances its ability to cross the blood-brain barrier.3

The glutathione I offer is acetylated in nanotechnology, making it even more bioavailable than other acetylated forms. Due to the complexity involved in the production of acetylated glutathione and nanotechnology, it tends to come at a much higher price. Your health is worth it. The acetylation process and microcluster molecular structure ensure that it won’t break down before your body absorbs it.

2. Curcumin

There’s a lot of hype around curcumin these days and for good reason. Curcumin, which comes from a highly concentrated extract of turmeric, plays a huge role in promoting a healthy inflammatory response, a healthy immune system, and healthy aging. Studies have shown that it is more effective at fighting inflammation than NSAIDs such as aspirin and ibuprofen, and it can positively impact the expression of genes that regulate systemic inflammation, which is a major factor in anyone with autoimmunity.4

Similar to glutathione, curcumin supplements are not well absorbed and often metabolized by your liver before being utilized. That’s why I recommend a fat-soluble form of curcumin. Since curcumin naturally dissolves in fat, taking it in a fat-soluble form allows it to remain intact until it can actually be absorbed by your cells.

A micelle formula of liposomal curcumin is the world’s most absorbable and bioavailable form of curcumin. My formula of Liposomal Curcumin has a potency of 500mg of naturally extracted curcumin per serving and solves the problem of poor absorbability and bioavailability with a thin layer of fat from medium-chain-triglyceride (MCT) oil. Your intestinal lining readily absorbs the micelle ‘pocket’ created by MCT oil that protects it from metabolism by your liver, so that it may travel freely throughout your body to the cells and tissues that need it the most.

3. Resveratrol

Resveratrol is the potent polyphenol found in red wine. Known for its anti-aging benefits, resveratrol stimulates production of SIRT1, a serum that blocks diseases by speeding up the cell’s energy production centers known as mitochondria.5 Research has shown that resveratrol can slow the progression of autoimmune diseases, such as rheumatoid arthritis, lupus, psoriasis, inflammatory bowel disease, and type 1 diabetes.6

Resveratrol is a powerful free radical scavenger. It neutralizes unstable molecules that can damage your cells, lead to premature aging, and trigger a leaky gut. It also helps modulate your immune system by regulating the activity of specific white blood cells called natural killer cells. This helps balance your immune response if your immune system is overactive or suppressed.

Resveratrol may also benefit heart health, which is essential because people with autoimmunity are more susceptible to heart disease. It helps protect the innermost layer of your arteries called your endothelium, and increases your endothelial production of nitric oxide, supporting balanced blood pressure.

Fortunately, you can get all of the health benefits of resveratrol without the sugar, alcohol, sulfites, and histamines found in red wine by taking a resveratrol supplement.

4. Immune Booster

Your immune system uses proteins called immunoglobulins, or antibodies, to fight off bacteria and viruses. There are four types of immunoglobulins (IgA, IgE, IgG, IgM) and they are the first line of defense in your gut, where nearly 80% of your immune system lives.

My autoimmune patients were often low in immunoglobulins. Many people find this surprising because they think that if they have an autoimmune disease then their immune system is TOO strong and that’s why it’s attacking them. In reality, the opposite is typically true, and their overstressed immune system attacks their own cells. Supporting your immune system, rather than suppressing it, is what’s important.

That’s why I recommend my Immune Booster supplement for patients dealing with autoimmunity. Immune Booster contains whey peptides from supercharged colostrum. It is a very special kind of mammalian milk produced only immediately after giving birth. It offers concentrated amounts of all four immunoglobulins to support immune function and your body’s normal gut repair pathways. Immune Booster also helps you maintain a healthy inflammatory response in your intestinal tract and colon.

If you have an autoimmune disease, I recommend you take this supplement all the time. However, everyone can benefit from Immune Booster, especially during the winter months. Your immune system tends to be more vulnerable to seasonal illnesses.

5. L-Glutamine

The last supplement I recommend to all of my patients with autoimmunity is L-Glutamine. L-glutamine is an amino acid that helps seal the tight junctions in your gut. Your gut cells naturally turn over every 48 hours, which is why it’s possible to repair your gut in 30 days following The Myers Way®. L-Glutamine works by speeding up that process and helping to restore your gut lining if you have a leaky gut.

As I lay out in my book, The Autoimmune Solution, repairing your gut is the first step to overcoming autoimmunity. Remember, nearly 80% of your immune system lives in your gut. Maintaining a healthy gut is key for anyone with an autoimmune condition. It’s why I always say the gut is the gateway to health!

In addition to promoting optimal gut health, L-Glutamine supports thyroid and immune system function. It also combats sugar cravings and supports healthy weight maintenance.

Ultimately, when you have an autoimmune disease, your best course of action is to support your immune system and help it do the work that will keep you healthy. There are many supplements available that could provide protection and relief to help you reverse your condition and take back your health. These are the top 5 supplements I recommend for autoimmune disease. They are just scratching the surface of how you can sustain your health and wellness!

Article Sources

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756154/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756154/
  3. http://glutathionepathway.com/types-of-glutathione/
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003001/
  5. http://science.sciencemag.org/content/339/6124/1216?sid=b369173a-02a4-4f5c-b693-4a1e4e870a4d
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748756/

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